Since the time of Hippocrates to the 20th century, stomach ulcers have been treated with acid-reducing medications because it was dogmatically believed that bacteria could not exist in an acidic environment. Not surprisingly, when doctors J. Robin Warren and Barry Marshall declared the Helicobacter pylori bacterium to be the true cause of most peptic ulcers, their assertion was met with disbelief and hostility. In this program, narrated by Blythe Danner, the crusade for acceptance of H. pylori as the leading cause of stomach ulcers is documented, including Dr. Marshall's unconventional measure of infecting and then curing himself. With the eventual acceptance of the Warren/Marshall research, ulcers are finally being permanently cured. Through the open-mindedness of two doctors, the quality of life for millions has been improved. (57 minutes)